diff --git a/CHANGELOG.md b/CHANGELOG.md
index 4b84e2a1c3..de4049c614 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -10,6 +10,8 @@ This project adheres to [Semantic Versioning](https://semver.org/).
 
 ## Fixed
 - [#3541](https://github.com/plotly/dash/pull/3541) Remove last reference of deprecated `pkg_resources`.
+- [#3520](https://github.com/plotly/dash/pull/3520). Set `pointer-events` to `auto` on `Tooltip` to make it possible to interact with tooltip content when `targetable=True`
+
 
 ## [3.3.0] - 2025-11-12
 
diff --git a/components/dash-core-components/src/components/Tooltip.react.js b/components/dash-core-components/src/components/Tooltip.react.js
index 005f48dfe8..9ba6a81ae4 100644
--- a/components/dash-core-components/src/components/Tooltip.react.js
+++ b/components/dash-core-components/src/components/Tooltip.react.js
@@ -83,7 +83,7 @@ const Tooltip = ({
                     background: ${background_color};
                     white-space: nowrap;
                     z-index: ${zindex};
-                    pointer-events: none;
+                    pointer-events: ${targetable ? 'auto' : 'none'};
                 }
                 .hover .hover-content,
                 .hover-right .hover-content {