Plugdata 0.9.2 in pop-os 22.04 with an AMD Ryzen 7 7840hs w/ Radeon 780 graphics. Screen have mixed refresh rates.
Problem observed:
Mouse clicks were commonly ignored when the Plugdata window was on an external display. Mouse clicks worked when the window was on the internal display or overlapping between displays. This was likely caused by vsync issues causing the mouse click to be missed during a UI "sleep" interval.
Solution:
"env vblank_mode=0" can be executed before launching plugdata from the terminal.
This uncouples the repaint timer from the refresh rate so all mouse clicks are registered. This might result in screen tearing.