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Performance discrepancy with nan coordinates vs coordinates=None

Status: Open.

#294 In evolutionaryscale/esm;

· jsjung00 opened on Dec 19, 2025

[Bug] API sends all hidden states when asked for only mean hidden state

Status: Open.

#292 In evolutionaryscale/esm;

· kumarshreshtha opened on Dec 7, 2025

esm3's train or finetune

Status: Open.

#290 In evolutionaryscale/esm;

· meiyiyeshi opened on Nov 29, 2025

Long protein sequence

Status: Open.

#289 In evolutionaryscale/esm;

· KhoiDang410 opened on Nov 10, 2025

Protein generation around active site without specifying residue numbers

Status: Open.

#288 In evolutionaryscale/esm;

· RobinFeng123 opened on Nov 8, 2025

ESMProtein.from_pdb() ignores HETATOM

Status: Open.

#287 In evolutionaryscale/esm;

· Ento0n opened on Nov 5, 2025

An error occurred when running Quickstart for ESM3-open. replace() argument 2 must be str, not None

Status: Open.

#285 In evolutionaryscale/esm;

· pdxooo opened on Oct 28, 2025

Wil the esmc-6b model be public available?

Status: Open.

#282 In evolutionaryscale/esm;

· ShaowenJCornell opened on Oct 16, 2025

Validate ESM3-VQVAE Scripts

Status: Open.

#277 In evolutionaryscale/esm;

· mahdip72 opened on Oct 3, 2025

How to enable batch training?

Status: Open.

#260 In evolutionaryscale/esm;

· yuliangyan0807 opened on Jul 30, 2025

Missing contact-regression model file for esmc_600m_2024_12_v0

Status: Open.

#259 In evolutionaryscale/esm;

· aowuawu opened on Jul 23, 2025

Dependency on torchtext

Status: Open.

#249 In evolutionaryscale/esm;

· leachim opened on Jun 14, 2025