Metadata File Format: Signatures

The signatures metadata file specifies the signature groups and where to find the signatures files. Each row corresponds to a signature group.

This file must be located at obj/meta-sigs.tsv

It consists of the following columns:

• Signature Group: The name for the group of signatures. Required.
• Publication: Text attributing the signatures to a specific publication.
• Path to Meta File: Path to the signatures metadata file. Relative to obj directory. Required.
• Path to Signatures SBS_96 File: Path to the SBS_96 signatures data file. Relative to the obj directory.
• Path to Signatures DBS_78 File: Path to the DBS_78 signatures data file. Relative to the obj directory.
• Path to Signatures INDEL_Alexandrov2018_83 File: Path to the INDEL_Alexandrov2018_83 signatures data file. Relative to the obj directory.
• Path to Cancer Type Map File: Path to the cancer type map file for the signature group. Relative to the obj directory.

The following is an example of this file:

Signature Group	Publication	Path to Meta File	Path to Signatures SBS_96 File	Path to Signatures DBS_78 File	Path to Signatures INDEL_Alexandrov2018_83 File	Path to Cancer Type Map File
COSMIC	Alexandrov L.B. et al., Nature 2013	signatures/COSMIC/processed/cosmic-signatures.meta.tsv	signatures/COSMIC/processed/cosmic-signatures.SBS-96.tsv			signatures/COSMIC/cancer_type_map.tsv
...	...	...	...	...	...	...